产品货号:
Z28515
中文名称:
TLR5抗体
英文名称:
Anti-TLR5 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-TLR5 Antibody |
指标别名 | SLEB1;TIL3;TLR5;toll like receptor 5 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC |
基因名称 | TLR5 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | TLR5 antibody was raised against a peptide corresponding to 16 amino acids near the center of human TLR5.The immunogen is located within amino acids 450 - 500 of TLR5. |
计算分子量 | 98kDa |
成分 | TLR5 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | TLR5 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila.These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection.TLR5 recognizes flagellin from both Gram-positive and Gram-negative bacteria and will cause the activation of NF-百B,leading to the activation of TNF-汐and other cytokines.A common TLR5 stop codon polymorphism that disrupts TLR5 signaling is associated with susceptibility to Legionnaires'disease and demonstrates the importance of TLR5 in the innate immune response. |
Uniprot ID | O60602 |
基因名全称 | Toll-like receptor 5 |
蛋白名全称 | Toll-like receptor 5 |
推荐稀释比 | TLR5 antibody can be used for detection of TLR5 by Western blot at 0.5 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 10μg/mL.Antibody validated:Western Blot in rat samples and Immunohistochemistry in rat samples.All other applications and species not yet tested. |
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